Transport of lysolecithin by albumin in human and rat plasma
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چکیده
منابع مشابه
Transport of lysolecithin by albumin in human and rat plasma.
Lysolecithin comprises 9.6 and 21.5% of the phospholipids of the plasma of man and rat, respectively. Ultracentrifugal and gel filtration studies showed that the major portion of the lysolecithin is not found together with the other phospholipids in the plasma lipoproteins. By zone electrophoresis, gel filtration, and ammonium sulfate fractionation, it was found that lysolecithin was consistent...
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There is in normal plasma an enzyme activity which converts labeled lysolecithin to lecithin by an energy-independent low density lipoprotein-activated pathway. Studies were undertaken to compare the identity of this enzyme with lecithin-cholesterol acyltransferase. During purification of the enzyme by ultracentrifugation and by chromatography on high density lipoprotein affinity column, DEAE-S...
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Human platelets incubated with 32p lysolecithin convert this compound to platelet lecithin and the water-soluble product glycerylphosphorylcholine. Lecithin synthesis from lysolecithin by intact platelets has a pH optimum of 9, whereas platelet homogenates show a pH optimum of 7.5 for the same reaction. Conversion of lysolecithin to platelet lecithin takes place by direct acylation of lysolecit...
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Background: Due to multiple roles of albumin in the body, injection of its medicinal product as one of the therapeutic or management strategies under conditions such as severe bleeding, burns, liver failure, and neonatal hemolytic diseases is on the physicians' agenda. Considering that albumin is the most abundant plasma protein, designing an appropriate method to purify it is highly important....
متن کاملCatabolism of plasma albumin by the perfused rat liver.
The liver is known to be a major site of plasmaprotein synthesis, but there is little information concerning its role in the catabolism of native plasma proteins. The ease with which the isolated perfused liver can be maintained under physiological conditions would appear to make it an ideal system for studying plasma-protein breakdown. However, the ability of the liver to take up particulate m...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 1965
ISSN: 0022-2275
DOI: 10.1016/s0022-2275(20)39614-0